ROOTED IN DERMATOLOGY AND HYDROTHERAPY Avène has over 270 years of expertise in caring for sensitive skin and is trusted by millions worldwide. At the heart of the brand is Avène Thermal Spring Water a natural soothing source clinically shown by over 150 studies to soothe soften and calm the skin.ROOTED IN DERMATOLOGY AND HYDROTHERAPY Avène has over 270 years of expertise in caring for sensitive skin and is trusted by millions worldwide. At the heart of the brand is Avène Thermal Spring Water a natural soothing source clinically shown by over 150 studies to soothe soften and calm the skin.